Development of Predictive Models for Continuous Flow Left Ventricular Assist Device Patients using Bayesian Networks

AUTHORS Natasha A. Loghmanpour, Manreet K. Kanwar, Raymond L. Benza, Srinivas Murali and James F. Antaki ABSTRACT Background: Existing prognostic tools for patient selection for ventricular assist devices (VADs) such as the Destination Therapy Risk Score (DTRS) and newly published HeartMate II Risk Score (HMRS) have limited predictive ability, especially with the current generation of continuous flow […]

Simulation of Dilated Heart Failure with Continuous Flow Circulatory Support

AUTHORS Yajuan Wang, Natasha Loghmanpour, Stijn Vandenberghe, Antonio Ferreira1, Bradley Keller, John Gorcsan, James Antaki ABSTRACT  Lumped parameter models have been employed for decades to simulate important hemodynamic couplings between a left ventricular assist device (LVAD) and the native circulation. However, these studies seldom consider the pathological descending limb of the Frank-Starling response of the overloaded ventricle. […]